Effects of nitrofurazone on spermatogenesis and reproductive toxicity in male rats. Part of a collaborative work to determine optimal administration period and endpoints.
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منابع مشابه
Collaborative work to determine an optimal administration period and optimal parameters for detection of effects on male fertility in rats--male reproductive toxicity study of haloperidol.
Haloperidol, a neuroleptic, was orally administered at 0, 3, 10, 30 and 60 mg/kg/day in a 4-week dosing study, and 0, 3, 10 and 30 mg/kg/day in a 9-week dosing study, to Sprague-Dawley male rats which were then sacrificed for histopathological examination or mated with untreated females. The males in the mating groups were continuously treated during the mating period. Sperm positive females we...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 1995
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.20.341